Postdoctoral positions are available immediately in the Yao lab at Emory University School of Medicine – to study Epigenetic modifications in neurodegenerative and psychiatric disorders

Postdoctoral fellows and research specialists positions will be available in 2018 in the laboratory of Dr. Bing Yao in the Department of Human Genetics at Emory University School of Medicine. The Yao laboratory has available research projects centering on understanding the pivotal roles of epigenetic marks in mammalian neurodevelopment and neuronal function, as well as how dysregulation of these marks contributes to brain disorders. We are particularly interested in dissecting the molecular mechanisms underlying the dysregulation of epigenetic modifications in the development and onset of neurodegenerative disorders such as fragile X-associated tremor/ataxia syndrome (FXTAS) and Alzheimer's disease (AD), as well as neuropsychiatric disorders such as major depressive disorder (MDD) and autism spectrum disorders (ASD). This work will combine genetics, genomics, neuroscience, molecular biology and bioinformatics to study these diseases using various models, including mouse, Drosophila, and human patient-derived iPSCs.

The trainee will receive extensive training in cutting-edge wet lab technologies, such as genome-wide epigenetic profiling coupled with high-throughput sequencing, transcriptome and proteomic analyses, CRISPR/Cas9, and iPSC differentiation. Additionally, the candidate will receive bioinformatics training in R/BioConductor and Unix-based python programming skills to analyze next-generation sequencing data. The fellow will also be trained in grant/manuscript writing, will have opportunities to present at scientific conferences, and will work closely with the PI for independent career development. The fellow will benefit from state-of-the-art research facilities and the thriving and collegial research environment, as well as excellent benefits offered by the Department of Human Genetics at Emory University School of Medicine.

We are looking for highly motivated postdoctoral fellows and research specialists who are interested in studying molecular mechanisms and genetics in human brain diseases to join our growing team. The successful candidate will be expected to exhibit a strong work ethic, independent initiative, and the ability to work both independently and as part of a team on research projects. For postdoctoral fellows, a Ph.D. in genetics, molecular biology, cell biology or neuroscience is required. Applicants with experience in mouse genetics and next generation sequencing technologies are preferred.

Applicants for the postdoctoral fellow should directly apply here and provide documents including a statement of research interest, a current CV and three references.

We will welcome PhD candidates for lab rotations at the beginning of 2018.

Whitehead Biomedical Research Building on Emory Campus (Yao Lab is in Rm 355 located in the 3rd floor)